Comprehensive Catalog of the Avian Gut Virome

AvianViromeDB represents the most comprehensive catalog of avian gut viromes to date, featuring 61,608 high-quality viral operational taxonomic units (vOTUs) assembled from 2,692 metagenomic samples across diverse avian species. This resource unveils extensive viral diversity and reveals the critical functional roles of bacteriophages in avian gut ecosystems.

Database Overview

2,692

Metagenomic Samples

From diverse avian species

61,608

Viral OTUs (vOTUs)

Species-level clusters (≥50% complete)

>95%

Potential Novel Families

Expanding known viral diversity

10,000+

Auxiliary Metabolic Genes

Potential host metabolic modulation

Scientific Insights

Unlocking Viral Dark Matter

Provides the most comprehensive view of avian gut viral diversity to date, identifying thousands of novel viral species and families previously unknown to science.

Mapping Functional Potential

Identifies a vast repertoire of Auxiliary Metabolic Genes (AMGs) involved in key pathways (e.g., carbohydrate, nucleotide metabolism) and clinically relevant Antibiotic Resistance Genes (ARGs).

Host-Virus Interaction Networks

Predicts putative bacterial hosts for thousands of viruses, offering insights into phage-bacteria dynamics and their potential regulatory roles within the gut ecosystem.

Download Database

Core Database Files

vOTU Sequences

Non-redundant viral operational taxonomic unit sequences.

(FASTA, ~523MB) vOTUs.fasta.gz

Protein Sequences

Predicted protein sequences from vOTUs in FASTA format.

(FASTA, ~348MB) vOTU_proteins.faa.gz

vOTU Annotations

Comprehensive metadata including quality metrics (CheckV), taxonomy (VITAP/geNomad), lifestyle (BACPHLIP), source host, completeness, etc.

Functional Gene Annotations

Predicted Auxiliary Metabolic Genes (VIBRANT/DRAM-v) and Antibiotic Resistance Genes (multi-database consensus) with associated vOTUs.

Host Predictions

Predicted bacterial host phyla and genera (iPHoP) for high-quality vOTUs.

Additional Resources

SQLite Database

Complete database with all annotations in SQLite format for easy querying and analysis.

(SQLite, ~477MB) AvianViromeDB.sqlite

Database description

Description of the database schema.

(PDF, ~6.2KB) db_description.txt